Application Of Apis dorsata Binghami Bee Nest Extract On The Effects Of Human Blood Lipid Reduction
DOI:
https://doi.org/10.53682/ibj.v2i2.3253Keywords:
Apis dorsata Binghami, antihyperlipidemia, forest beehive teabags, people group testAbstract
Honey, royal jelly, bee pollen, bee wax, propolis, bee glue, and bee venom/ apitoxin are among the items produced by honey bees. Honey, pollen, bees, eggs, larvae, and pupae are all stored in the A. dorsata Binghami beehive. Secondary metabolites and bioactive phenolic compounds (phenols, phenolic acids, esters, flavors, dihydroflavones, flavanols, chalcones, and phenolic glycerides), essential oils (mono and sesquiterpenes), polysaccharides, amino acids, amines, lactones, quinones, steroids, and vitamins) can all be found in honeycomb. The goal of this study is to see how A. dorsata Binghami honeycomb tea affects blood lipid levels in humans after 14 days of consumption in a small group of male and female volunteers who were given a 2 gram tea bag extract of A. dorsata Binghami honeycomb simplicia to drink once a day to see how it affects lipid levels (total cholesterol, LDL, HDL, and TAG) in human blood. Total cholesterol (140.56 mg/dL), triglycerides (140.93 mg/dL), LDL (85.92 mg/dL), and HDL (21.49 mg/dL) were all found to be high in humans. As a result, "The Use of A. dorsata Binghami's Honeycomb Extract on the Effect of Reducing Human Blood Lipids" can lower lipid levels.
References
Bawa KS. 1990. Plant-pollinator interactions in tropical rain forest. Annu Rev Ecol Syst 21:399-422.
Beaurepaire AL, Kraus BF, Koeniger G, Koeniger N, Lim H, Moritz RFA. 2014. Extensive population admixture on drone congregation areas of the giant honey bee, Apis dorsata (Fabricius, 1793). Ecol and Evol 4(24):46694677. doi:10.1002/ece3.1284.
Bernardino AS, Gaglianone MC. 2008. Nest distribution and nesting habits of Xylocopa ordinaria Smith (Hymenoptera, Apidae) in a resting area in the northern rio de Janeiro State, Brazil. Revis Brasil Entomol. 52(3):434-440.
Bertoni R. 2013. Comparison of the size of the body parts of the Bee Apis Dorsata worker (forest bee) in four locations. thesis. BOGOR (ID). Bogor Agricultural Institute.
Damus, M.S. and G.W. Otis.1997. A morphometric analysis of Apis cerana F and Apis nigrocincta Smith populations from Southeast Asia. Apidologie 28: 309323.
Dyer FC. 1985. Nocturnal orientation by the asian honey bee, Apis dorsata. Animal Behavior. 33:769–774
Engel MS. 2012. The honey bees of Indonesia (Hymenoptera: Apidae). Treubia. 39:41-49
Fajaryanti, N., Nurrochmad, A., Fakhrudin, N. 2016. Evaluation of Antihyperlipidemic Activity and Total Flavonoid Content of Artocarpus altilis Leaves Extracts. International Journal of Pharmaceutical and Clinical Research. 8(5)Suppl: 461-465.
Gould, J.L. and C.G. Gould. 1988. The Honey Bee. New York: W.H. Freeman and Co.
Hadisoesilo, S., G.W. Otis, and M. Meixner. 1995. Two ditinct populations of cavity-nesting honey bees (Hymenoptera: Apidae) in South Sulawesi, Indonesia. J. Kansas Entomol. Soc. 68: 399-407
Hadisoesilo, S. 1997. A comparative studies of two species of cavity-nesting honey bees of Sulawesi, Indonesia. Ph.D. thesis, University of Guelph, Ontario, Canada.
Hadisoesilo. 2001. Diversity of original honey bee species in Indonesia. Center for Forest Research and Development and Nature Conservation, Bogor.
Hegazi AG. 1998. Propolis an overview. J Bee In¬formed, 5, 22-28.
Heldt, J and D. Heldt. Plant biochemistry. Elsevier, London, 2005.
Hepburn R, Radloff SE. 2011. Honeybees of Asia. New York (US). Springer-Verlag Berlin Heidelberg.
Kahono S, Nakamura K, Amir M. 1999. Seasonal msigration and colony behavior of the tropical honeybee Apis dorsata F. (Hymenoptera: Apidae). Treubia. 31(3)283-297.
Hegazi AG. 1998. Propolis an overview. J Bee In¬formed, 5, 22-28.
Heldt, J and D. Heldt. Plant biochemistry. Elsevier, London, 2005.
Hepburn R, Radloff SE. 2011. Honeybees of Asia. New York (US). Springer-Verlag Berlin Heidelberg.
Kahono S, Nakamura K, Amir M. 1999. Seasonal msigration and colony behavior of the tropical honeybee Apis dorsata F. (Hymenoptera: Apidae). Treubia. 31(3)283-297.
Krisnansari D, Hapsari A. T, Sulistyoningrum E, Prastowo A. 2012. Effect of Propolis against Pro Fi L Lipid Plasma Mice Model Hypercholesterolemia. Indonesian Clinic Nutrition Journal Vol. 8, No. 3, January 2012: 106-112
Kumazawa S, Hamasaka T, & Nakayama T. 2004. An¬tioxidant activity of propolis of various geo¬graphic origin. Food Chemistry, 84, 329-339.
Mokosuli YS, Kanuang ESN, and Manopo JS. Biopharmaca Development Antihiperlipidemia Extract Nest Api Dorsata Binghami Honey Bee Endemic Sulawesi. [DRPM research report]. Research Institute of Manado State University, 2018.
Mokosuli YS, Pelealu J, Tulung M, Mandey LC. Pharmacological Bioactivity Honey Bee Venom Apis nigrocincta Smith and A. dorsata Binghami Endemic to North Sulawesi. International Journal of Science and Engineering Investigations. 2013; 2(18):25-33.
Mokosuli YS, Mege RA, Versya G, Rompas C. The antihyperlipidemic activity of Apis dorsata Binghami nesting extract in atherogenic dietinduced hyperlipidemic rats. International Journal of Botany Studies ISSN: 2455-541X; Impact Factor: RJIF 5.12 Received: 21-05-2019; Accepted: 24-06-2019 www.botanyjournals.com Volume 4; Issue 4; July 2019; Page No. 174-178.
Mosquera OM, Correa YM, Buitrago DC, Nino J. 2007. Antioxidant activity of twenty five plants from Colombian biodiversity. Mem Inst Oswaldo Cruz 102(5):631-634.
Neumann P, Koeniger N, Koeniger G, Tingek S, Kryger P, Morits RFA. 2000. Home-site fidelity of migratory honeybees. Nature. 406:474-475.
Neupane KR, Woyke J, Poudel SM. 2013. Nesting site-preference and behavior of giant honey bee Apis dorsata. Paper presented on Apimondia, 29 September-4 October 2013 , Kyiv, Ukraine and published on abstract and working procedure Apimondia, 2013.
Oldroyd BP, Nanork P. 2009. Conservation of asian honeybees. Apidologie. 40: 296-312.
Raffiudin R. Honey bee behavioural evolution and itpr gene structure studies. [PhD Thesis]. James Cook University http::eprints.jcu.edu.au/1249, 2002.
Raffiudin R, Crozier R. H. 2007. Phylogenetic analysis of honeybee behavioral evolution. MPE. 43:543-552.
Ruttner, F. 1988. Biogeography and Taxonomy of Honeybees. Springer-Verlag, Berlin.
Ruttner, F. 1992. Naturgeschichte der Honigbienen. Munich: Ehrenwirth Verlag. Ruttner, F., D. Kauhausen, and N. Koeniger. 1989. Position of the red honey bee, Apis koschevnikovi (Buttel-Reepen, 1906), within the genus Apis. Apidologie 20: 395-404.
Sakagami FS, Matsumara T, Ito K. 1980. Apis laboriosa in Himalaya, the little known world largest honeybee (Hymenoptera:Apidae). Insect Matsum. 19:47-77.
Seeley TD. 1985. Honeybee Ecology A Study of Adaptation in Social Life. Princeton University Press. Princeton, New Jersey, United Kingdom
Starr CK, Schmidt PJ, Schmidt JO. 1987. Nest site-preferences of the giant honey bee, Apis dorsata (Hymenoptera: Apidae), in Borneo. Pan Pasific Entomol. 63(1):37-42.
Suranto Adji., Dahsyatnya Propolis untuk Menggembur Penyakit (Jakarta: Agromedia Pustaka, 2010)
Zhu Qin Yan, Yu Huang, Zhen-Yu Chen. Interactions between Flavonoids and α-Tocopherol in Human Low Density Lipoprotein. J. Nutr. Biochem. 2000; (11):14-21.