POTENTIAL ANTIBACTERIAL EXTRACTS OF MANGROVE GENUS AVICENIA ROOT AND LEAVES FROM KOMBI BEACH MINAHASA
DOI:
https://doi.org/10.53682/ibj.v2i3.4985Keywords:
antibacterial, crude extract, leaf, aviceniaAbstract
This study aimed to obtain the phytochemical content of the crude extract of leaves and roots of Avicenia spp from Kombi Beach Minahasa. Obtaining data on the activity of inhibiting the growth of infective microbes on external wounds of crude extract of leaves and roots of Avicenia spp from Kombi Beach, Minahasa. To determine the concentration of minimum growth inhibition of crude extract of leaves and roots of Avicenia spp from Kombi Beach, Minahasa. Knowing the crude extract (crude extract) leaves and roots of Avicenia spp originating from the Minahasa Kombi Beach is bactericidal or bacteriostatic. This research consisted of extraction, phytochemical analysis and antibacterial activity test. The results showed that the dominant secondary metabolites in the root and leaf extracts were alkaloids, flavonoids, saponins and tannins. The chloroform extract inhibited the growth of bacteria in infected wounds more than the ethanol and n-hexane extracts, at concentrations of 15 and 30 ppm for the test solution of ethanol extract with an inhibitory diameter of < 7 mm and a concentration of 50 ppm with an inhibitory diameter of > 10 mm indicating that the high bioactive activity antibacterial.
References
Akarele JA. 2008. Antimicrobial Activity Of The Ethanol Extract And Fractions Of The seeds Of Garcinia kola Heckel (Guttiferae). Afr. J. Biotechnol. Vol. 7 (2):169-172.
Bidiarso R. 1996. Survey Kesehatan Rumah Tangga. Jakarta : Badan penelitian dan Pengembangan Kesehatan DepKes RI.
Ajijah A. 2004. Sensitivitas Salmonella typhimurium Terhadap Ekstrak Daun Psidium guajava. Bioscientiae Volume 1(1):31-38.
Cutisurb surbact . 2007. Pencegahan Pada Luka Trauma Superfisial. PT BSN Medical Indonesia
Djulkarnain,dkk. 2009. Tanaman Obat Bersifat Antibakteri.
Hartini, dkk. 2006. Daya Antibakteri Campuran Ekstrak Etanol Buah Adas (Foeniculum Vulgare Mill) Dan Kulit Batang Pulasari (Alyxia Reinwardtii Bl). Jurnal Farmasi. hal 191-196
Irobi ON Mon-Young, Anderson WA (1996). Antimicrobial activity of Annatto (Bixa orellana extract). Int. J. Pharm Vol.34:87-90
Mokosuli YM. 2008. Aktivitas Antioksidasi Dan Antikanker Ekstrak Kulit Batang Langsat (Lansium domesticum L.) [Tesis]. SPS Institut Pertanian Bogor.
Noor, dkk. 2006. Analysis of Secondary Compounds and Testing of Antibacterial Activity of Minusops elengi L Extract on Salmonella typhi and Shigella boydii. Seminar Nasional Teknologi Peternakan dan Veteriner pp.986-992.
Parwata, dkk. 2008. Isolasi Dan Uji Aktivitas Antibakteri Minyak Atsiri Dari rimpang Lengkuas (Alpinia galanga l.). Jurnal Kimia 2(2):100-104
Pholoengan, dkk. 2006. Aktivitas Antimikroba Dan Fitokimia Dari Beberapa Tanaman Obat. Seminar Nasional Teknologi Peternakan dan Veteriner 2006 (pp. 974-978).
Rasional. 2001. Antibakteri. Media Informasi Peresepan Rasional Bagi Tenaga Kesehatan Indonesia. Vol.2(1).
Russel AD, Fur JR (1997). Antibacterial activity of a new chloroxylenol prepration containing ethylenediamine tetra acetic acid. J. Appl. Bacteroil 43: 253-260.
Salvador, N. A. G. Garreta, L. Lavelli and M. A. Ribera. 2007. Antimicrobial Activity of Iberian Macroalgae. Scientia Marina, vol.1:101-113
Tuney, Inci., B. H. Cadirci, D. Unal and A. Sukatar. 2006. Antimicrobial Activities of the Extracts of Marine Algae from the Coast of Uria (Izmir, Turkey). Turk J Biol vol.30:171-175